The Great British Bake Off judge supports the campaign for law change in the UK after seeing her brother David, 74, suffer before he died from bone cancer in 2012.
A family twist is her son Danny Kruger, MP for Devizes in Wiltshire, is among its most vocal opponents.
Yet Dame Prue, 83, will speak at a Holyrood reception today for Liam MacArthur MSP in support of his Assisted Dying for Terminally Ill Adults Bill.
She said: “I’d love to know I had an option to end my life if I wanted to because I was in unbearable pain. I’m not trying to make the world kill themselves. I just want people to have the choice when they are terminally ill. If you’ve had a good life, do you really want to spend the last six weeks of it hating it and being unable to leave?”
Dame Prue and Danny, 49, made a documentary on the issue this year, travelling around the US visiting places where it is legal. The Express Give Us Our Last Rights crusade also backs calls for law change.